Bioreactor for cell culture BioAxFlow

Bioreactor suitable for cell culture experiments on scaffolds of different geometries, implemented with continuous medium circulation.

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Description

The purpose of this bioréactor is to continuously pump the cell culture medium into the vessel from the bottom, lifting the cells up, accessing the vessel and, eventually, allowing cell seeding on the scaffold, with the help of an external peristaltic pump. It is a complete “plug and play” solution for tissue engineering, combining innovation, versatility, and ease of use.

The 4 main components of the bioreactor

  • The base that allows both medium entry and exit thus, generates fluid dynamics suitable for efficient cell culture within the bioreactor chamber;
  • The scaffold stand designed to accommodate constructs/scaffolds of different geometries and sizes, customisable by the client;
  • The glass cylinder, allowing for constant visual inspection of the content;
  • The cap is equipped with sampling ports for cell sampling and threaded supports for vent plugs.

Advantages of the bioreactor for cells culture

  • Construct and scaffold can have different geometries and dimensions. The design and production is customisable
  • It allows automated cell seeding via the utilization of simple control valves.
  • It achieves a homogeneous cell distribution. The generation of its sophisticated fluid dynamics, allows cells to be distributed homogeneously upon the scaffold.
  • The bioreactor is modular and can incorporate more than a single fully integrated bioreactor, to perform multiple experiments in parallel.
  • Fully transparent vessel for optical investigations.
  • Suitable for suspension and anchorage-dependent cell culture
  • Available for volumens from 10 mL to 200 mL